Her performance as the title character in the HBO biopic Temple Grandin earned her an Emmy, a Golden Globe, a Satellite and a Screen Actors Guild Award.
She married Hugh Dancy in 2009. She had her first child, a son named Cyrus, in 2012. They welcomed a second son in 2018. In January 2023, they announced they were expecting their third child together. They welcomed a daughter in July 2023.